Laboratory

The analytical specialisations of the Department of Instrumental Analysis are divided into three laboratories: LC-MS, GC-MS and NMR.

The LC-MS area covers a particularly broad scope of applications. Small to large analytes with a wide range of chemical properties are determined. From sample preparation and development to method validation (if requested by the customer), analysis and evaluation, we analyse substance classes.

Research

In addition to the three main areas of our laboratory also has the following analytical instruments:

Gas chromatography (GC) with FID and WLD
Head-space GC
HPLC and UHPLC with conventional detectors (DAD, ELSD, CAD, ECD, FLD)
Atomic spectroscopy (AAS) and ICP-OES
Automated HPTLC system and a TLC-MS interface

Focal points of analysis

Our analysis specialisms cover a wide range of topics. In addition to the development and validation of analytical methods, we also analyse main components as well as impurities and residues. For our customers we also work on problems that deal with structure elucidation, carrying out both targeted and non-targeted analyses. The processing of various matrices (natural substances, blood to pharmaceutical products) and associated problems are a key part of our work.

External collaborations

We work with companies and other universities, on internal projects across groups as well as with students. Further main topics are:

Analytical consulting
Literature and patent research
Metabolic profiling (method development including sample preparation, differentiation, mass spectrometry with statistical data analysis)
Protein and peptide analysis
Metabolites and xenobiotics in body fluids
Flavourings etc.