Alternative RNA splicing is a regulatory cellular mechanism to create multiple mRNA molecules from the same gene and is often disrupted in diseases. We could show in the international Pan-Cancer Analysis of Whole Genomes (PCAWG) study that such disruptions in alternative splicing patterns are widespread in cancer. By developing new…

The progression of multiple sclerosis (MS) is characterized by the evolution of brain lesions. Traditionally, neuroradiologists need to manually track and compare a large number of lesions in MRI images over multiple exams. Novel AI methods support this process, by automating the detection, localization, and quantification of lesions. WebJazz is a web application that makes…

To start the design of an orthosis or of a prosthesis, orthopedists commonly use plaster casting to acquire the patient’s limb shape. The rest of the design workflow is so far already digital. However, the limb shape acquisition is still analog, wet, inaccurate and time consuming. The Swiss startup BellwaldTec…

Early and accurate disease diagnosis is crucial for stopping disease progression and identifying appropriate treatments, but precise diagnosis of autoimmune disease is notoriously challenging due to the non-specific symptoms: it can take 4 to 5 years and multiple visits to various physicians. However, an early and precise disease diagnosis is…