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Biology, Medicine

Systematic meta-analysis revealing a potential for targeted and personalized cancer therapeutics

The use of many anticancer drugs is problematic due to severe adverse effects. While the recent clinical launch of several kinase inhibitors led to tremendous progress, these targeted agents tend to be of non-specific nature within the kinase target class. A future strategy will be the development of nanocarrier-based systems…

Biology, Medicine

Clinical, Laboratory and Multi-Omics Data to Leverage Machine Learning for Personalized Diagnostics

Early and accurate disease diagnosis is crucial for stopping disease progression and identifying appropriate treatments, but precise diagnosis of autoimmune disease is notoriously challenging due to the non-specific symptoms: it can take 4 to 5 years and multiple visits to various physicians. However, an early and precise disease diagnosis is…

Medicine

ICU Cockpit – Learning from Real-time Data Streams in the Intensive Care Unit

In today’s intensive care units (ICUs), biosensors collect up to 100 GB of data per patient every day. These vast amounts of data are only valuable if they lead to better patient outcomes. The following questions arise:How can medical staff gain insights from this data?How can risk constellations be identified as early as…

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