BioInterfaces

Engineered nanoparticles and interfaces for modulation and monitoring of biological systems.

Team leader BioInterfaces: Prof. Dr. Oya Tagit

Nanoparticles precisely engineered at the nanoscale have emerged as novel therapeutic and diagnostic agents due to their unique physicochemical properties (e.g. optical, magnetic, electronic, etc.) that are dictated by their size, shape, composition, surface; and can be customized for the desired biological targets and functions. With applications ranging from imaging and detection probes to nanocarriers for (bio)therapeutics delivery, engineered nanoparticles can give unprecedented information on the chemical and physical processes that take place in biological systems, and enable targeted therapeutic interventions.
In the group of BioInterfaces, we aim to address currently unmet biomedical needs in the diagnosis, monitoring, and treatment of disease with engineered nanoparticles tailored for the desired biological targets and functions. We utilize an interdisciplinary approach at the interface between materials chemistry, nanotechnology, and biology for bench-to-bedside development of optical and magnetic detection probes, (pre-)clinical imaging agents, and drug delivery systems based on inorganic and polymeric nanoparticles. We study the diagnostic and therapeutic performance of these nanoparticles in vitro and in vivo using advanced imaging and cell culture techniques and disease models.

Prof.Dr. Oya Tagit, Head of the Group
Anamarija Nikoletic
PhD candidate
Dr. Evangelos Natsaridis Postdoc
Dr. Michel-Angelo Sciotti
Senior Scientist
Nadya Stebler
MSc thesis
Dr. Samuel Lörcher
Visiting Researcher
Dr. Daiane Quadros
Visiting Researcher

M-SLS-MSc 0223 Molecular and Translational Imaging

M-SLS-F Biomarker

In the group of BioInterfaces, we aim to address currently unmet biomedical needs in the diagnosis, monitoring, and treatment of disease with engineered nanoparticles tailored for the desired biological targets and functions. We utilize an interdisciplinary approach at the interface between materials chemistry, nanotechnology, and biology for bench-to-bedside development of optical and magnetic detection probes, (pre-)clinical imaging agents, and drug delivery systems based on inorganic and polymeric nanoparticles. We study the diagnostic and therapeutic performance of these nanoparticles in vitro and in vivo using advanced imaging and cell culture techniques and disease models.

Projects & News

ICB news, BioInterfaces

Best Poster Prize for Anamarija Nikoletic

Anamarija Nikoletic, PhD candidate at the Group of Biointerfaces led by Prof. Dr. Oya Tagit, received the best poster prize at the Swiss Nanoscience Institute Annual Event. In her SNI PhD School project entitled “Multi-compartment nanofactories for on-site and on-demand drug synthesis and delivery”, Anamarija aims to develop triggerable, compartmentalized vesicles…

ICB news, BioInterfaces

Welcome to Nada Ghabach

Nada joined the ICB on September 1st. Find out about her research activities and interests here.

ICB news, BioInterfaces

Welcome to Marta Maria Alves Pereira

Marta Maria Alves Pereira PhD candidate Ms Marta Maria Alves Pereira has been awarded a scholarship from the CAPES Foundation, an agency under the Ministry of Education of Brazil, to spend one month at the Group of Biointerfaces led by Prof. Dr. Oya Tagit. Marta will develop and characterize…

Projects, BioInterfaces

Novel biocompatible and biodegradable polymers for biomedical applications

We design novel bio-based polymers to develop biocompatible and biodegradable nanocarriers as alternatives to e.g. PEG.

Projects, BioInterfaces

Multi-compartment nanofactories for on-site and on demand drug synthesis and delivery

We develop compartmentalized vesicles with internal compartments that can be triggered independently and selectively to release their cargo. Libraries of novel stimuli-responsive block co-polymers are prepared for vesicle formation, and release is actuated by external stimulus such as light, magnetic field, etc.

All projects & news of this group

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