Projects
Projects of the Institute for Pharma Technology.
All Projects of the Institute for Pharma Technology in alphabetical order.
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A new dynamic light scattering technique to analyze dispersions
Introduction of a new modulated 3D cross-correlated dynamic light scattering instrument to enable product analytics of aggregating colloids and concentrated dispersions
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A race against time
Whether or not a drug helps, depends on more than just its active ingredient. That ingredient first has to get to the place where it needs to work. The new targeted drugs, however, require larger and more complex molecules. As a result, they are often poorly soluble and difficult to get from the gastrointestinal tract into the bloodstream. Therefore the HLS pharmacist Martin Kuentz is working on a reliable lipid-based system to transport poorly soluble drugs in dissolved form in the gastrointestinal tract.
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Bio-enabling formulations
Research and development on bio-enabling formulations as part of the EU-project PEARRL
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EASY
Easy Assessment of SolubilitY with high efficiency second harmonic light scattering
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InPharma
InPharma has the goal of eliminating animals from the development of new oral drug formulations (EU funds MSCA-H2020 EID InPharma)
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Intestinal drug absorption
Bio-conjugation combined with efflux in the enterocyte determines intestinal drug absorption
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Robot assistance in the laboratory
A great many experiments are required before a medicinal substance can become a finished drug. Researchers must find the best combination of stabilisers and other additives and test whether a drug always works as intended. This process can be facilitated with an HLS robot system which enables reliable studies to be done on highly sensitive biomolecules. A newly developed software tool provides a clear overview of the results of individual experiments, thus accelerating the search for the optimal drug formulation.